Viva Questions From Paget's Disease: Bone Diseases

Q. What is Platybasia?
- Descent of cranium onto the cervical spine

Q. Radiographic differential diagnosis of paget's disease:
- Cotton wool appearance;
1. Osteosarcoma
2. Fluid cemento-osseous dysplasia
3. Sclerosing osteomyelitis
4. Acute osteopetrosis

Q. Why there is rise in skin temperature of affected bone in Paget's disease?
- Abnormal and excessive remodelling of bone
                         ↓
initially increased osteoclastic activity
                         ↓
followed by accelerated but abnormal bone formation
and increased vascularity of bone combined with cutaneous vasodilatation
                         ↓
cause increase in regional blood flow
                         ↓
rise in skin temperature of affected bone

Q.Why there is "jig saw" or "mosaic" pattern of bone histologically in Paget's disease?
- Due to basophilic reversal lines because of continuous resorption and formation of bone.